Risk Factors of Bleeding among Patients with Acute Leukemia

Document Type : Original Article

Authors

1 Nursing Specilalist at South Eygpt Cancer Institute, Egypt.

2 Professor of Medical-Surgical Nursing, Faculty of Nursing, Assiut University, Egypt.

3 Assistant Professor Medical Oncology, South Egypt Cancer Institute, Assiut University, Egypt.

4 Assistant Professor Medical-Surgical Nursing, Faculty of Nursing, Assiut University, Egypt.

Abstract

Background: Patients with acute leukemia are at high risk for bleeding. Early recognizing these risk factors is crucial for preventing serious complications. Aim: To identify the risk factors of bleeding among patients with acute leukemia Design: Descriptive exploratory research design. Subjects and setting: Seventy-six 76 patients with acute leukemia admitted in Medical Oncology Department at South Egypt Cancer Institute. Tools: Tool (I): Patient assessment sheet; (1): Demographic data, (2): Clinical data, (3): Bleeding risk factors, (4): Laboratory investigations and tool (II): WHO bleeding scale. Results: Revealed the  mean age of studied patients was 40.22 years, (60.5%) were  males, (60.5%) diagnosed with AML. Fatigue (73.7%) and fever (71.1%) were the most commonly reported symptoms. According to WHO bleeding scale, The majority of patients categorized as grade 2 (44.7%) followed by grade 0 (32.9%) and grade 3 was (22.4%). Factors such as hypertension, diabetes mellitus, previous history of bleeding, thrombocytopenia, disseminated intravascular coagulation and smoking showed statistically significant relationship with higher WHO bleeding grades  (p < 0.5) Conclusion: The bleeding severity in acute leukemia patients was significantly associated with factors such as prior bleeding, hypertension, diabetes, smoking, thrombocytopenia, and disseminated intravascular coagulation, highlighting the importance of early identification and management of these risks. Recommendations: The critical importance of early identification and proactive management to prevent bleeding severity in acute leukemia patients and improve patient outcomes.

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